Effect of hydrogen injected subcutaneously on testicular tissues of rats exposed to cigarette smoke.

作者: Chen S, Jiang W
成果类型: 期刊论文
数据来源: ESI SCIE
发表日期: 2015
年卷期页: 2015,8,(4),5565-70
期刊名: 《International journal of clinical and experimental medicine》 影响因子和分区 年份    影响因子    区号
2017    0.833        2016    1.069        2015    1.075        2014    1.277       
英文关键词: Hydrogen;cigarette smoke;testicles
英文摘要: Smoking is one of the most common reasons inducing reactive oxygen species in semen. High concentration of active oxygen will cause decrease of sperm density and viability and induce oxidative injury of sperm DNA which has become the hot spot in male infertility. Although hydrogen was found to be an effective remover of active oxygen in liver, heart, kidney and brain, the same effect has not been discussed in reproductive system. The aim of this study was to investigate the protective effect of hydrogen against cigarette smoke-induced damage in rat reproductive system. Adult male Wistar rats were randomly divided into four groups to conduct this experiment, results showed that rats in SK+HSI group (passive smoking and hydrogen subcutaneous injection group) exhibited larger amount of sperm count, smaller sperm deformation rate, higher levels of testosterone and SOD in serum and testis, lower levels of MDA in testis and less morphologic abnormalities compared to SK+NSI group (passive smoking and nitrogen subcutaneous injection group). As a consequence, we concluded that injected subcutaneously exerted protective effects on reproductive system injury of male rats exposed to cigarette smoke through inhibiting oxidative damage.
语言: United States
出版类型: Journal Article
作者地址: Department of Urology, Zhongnan Hospital of Wuhan University Number 169, Donghu Road, Wuhan, Hubei, P.R. China ; Traditional Chinese Medicine, Chengdu University of TCM China. [1]
Traditional Chinese Medicine, Chengdu University of TCM China. [2]
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